957: Inherited variants in genes somatically mutated in thyroid cancer

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Inherited variants in genes somatically mutated in thyroid cancer

BACKGROUND Tumour suppressor genes when mutated in the germline cause various cancers, but they can also be somatically mutated in sporadic tumours. We hypothesized that there may also be cancer-related germline variants in the genes commonly mutated in sporadic well-differentiated thyroid cancer (WDTC). METHODS We performed a two-stage case-control association study with a total of 2214 case...

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ژورنال

عنوان ژورنال: European Journal of Cancer

سال: 2014

ISSN: 0959-8049

DOI: 10.1016/s0959-8049(14)50849-0